ABSTRACT:
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine illness that affects people of reproductive age and is characterized by a variety of clinical, hormonal, and metabolic aspects. This review article aims to provide a comprehensive overview of the PCOS epidemiology, aetiology, clinical presentation, diagnostic standards, and therapeutic choices. Worldwide estimates of PCOS prevalence among women of reproductive age range from 5% to 20%. This syndrome is well known for being complex in nature, encompassing both genetic predisposition and environmental influences. Menstrual abnormalities, hyperandrogenism, and an ultrasound showing polycystic ovarian morphology are frequent clinical symptoms. Several sets of diagnostic criteria, such as the Rotterdam criteria and the National Institutes of Health standards, are available, but accurate diagnosis is still essential. Insulin resistance, dyslipidemia, and obesity are among the metabolic disorders that are more likely to develop in people with PCOS. Long-term health effects include an increased risk of type 2 diabetes, cardiovascular disease, and infertility. Improvements in hormonal imbalances, metabolic abnormalities, and fertility outcomes are the main goals of therapeutic interventions, which are individualized to the patient's presentation and goals and include both lifestyle changes and pharmaceutical therapies. this review collects the most recent research results and clinical insights to enhance the understanding of PCOS among healthcare professionals.
Cite this article:
Shivaleela S. Sarawad. Polycystic Ovary Syndrome (PCOS): A Comprehensive Review. International Journal of Advances in Nursing Management. 2023; 11(4):264-5. doi: 10.52711/2454-2652.2023.00059
Cite(Electronic):
Shivaleela S. Sarawad. Polycystic Ovary Syndrome (PCOS): A Comprehensive Review. International Journal of Advances in Nursing Management. 2023; 11(4):264-5. doi: 10.52711/2454-2652.2023.00059 Available on: https://ijanm.com/AbstractView.aspx?PID=2023-11-4-11
REFERENCES:
1. Azziz R, Carmina E, Chen Z, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016; 2: 16057.
2. Diamanti-Kandarakis E, Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev. 2012; 33(6): 981-1030.
3. Stein IF, Leventhal ML. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol. 1935; 29(2): 181-191.
4. Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev. 1997; 18(6): 774-800.
5. Domecq JP, Prutsky G, Mullan RJ, et al. Lifestyle modification programs in polycystic ovary syndrome: systematic review and meta-analysis. J Clin Endocrinol Metab. 2013; 98(12): 4655-4663.
6. Teede HJ, Misso ML, Costello MF, et al. International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Clin Endocrinol (Oxf). 2018; 89(3): 251-268.